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Health library/Clostridioides difficile infection

Infections

Clostridioides difficile infection

Also known as: Clostridioides difficile infections, Clostridium difficile Infections, Clostridium enterocolitis, Pseudomembranous colitis

Clostridioides difficile can cause intestinal inflammation and diarrhea, often after antibiotic exposure. Some infections become severe or recur after recovery.

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What you may notice

Symptoms can overlap with other conditions and vary between people.

  • Watery diarrhea
  • Abdominal pain
  • Fever
  • Loss of appetite

Understanding care

Clinical care may include prompt clinical assessment, suitable testing and a clinician-led treatment plan. A qualified clinician decides which investigations and options fit the individual situation.

When to seek help

Seek prompt advice for significant diarrhea, especially after antibiotics or hospital care. Severe abdominal pain, fever, marked dehydration or rapidly worsening illness needs urgent assessment.

For severe breathing difficulty, collapse, suspected stroke, or another emergency, call local emergency services immediately. In India, call 112.

Read the medical sources

These sources support the educational article and offer more detail.

Educational reading · Updated 6 October 2026

Prepared from the linked sources. This summary has not had an independent clinician review. A qualified clinician can assess symptoms and explain which information applies to you.

A child and a caring grown-up reading a picture book together

LITTLE PEOPLE. BIG FEELINGS.

It’s okay to have
a lot of questions.

A doctor visit or an unfamiliar health word can feel scary. You can ask a trusted grown-up to help you understand, one small question at a time.

01

Say how you feel.

“I feel worried” is a good place to start.

02

Ask for simple words.

“Can you explain that in a way I understand?”

03

Bring someone you trust.

A caring adult can help you ask and listen.

For children and their grown-ups. This illustration explains a conversation, not a diagnosis. An adult should seek qualified care for a child who is unwell.

Clostridioides difficile infection — First AID health library